Rabbit Anti-SAP30L Antibody from MyBioSource.com

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Rabbit Anti-SAP30L Antibody

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The Rabbit Anti-SAP30L Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SAP30 like, and SAP30L. This antibody recognizes Human antigen. The Rabbit Anti-SAP30L Antibody has been validated for the following applications: Western Blot.

Description

A novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells